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Cytotoxic T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 6994

• Most cells which have CD8 on their surface become cytotoxic T cells (Tc cells). • CD8 T cells recognize a foreign antigen when it is presented in conjunction with the protein, MHC-I. • Nearly all nucleated cells in the body express MHC-I molecules. • T cells that recognize self-pe...

Cell mediated immune response to a viral infection Animation

By: HWC, Views: 2689

Intracellular pathogens are the targets of cell-mediated immune response. The process begins when a virus infects a macrophage. Another macrophage engulfs the same virus or an antigen from it. In both cells, enzymes cleave the viral antigens into small bits. The fragments move to the cell sur...

Immune responses Animation

By: HWC, Views: 3526

Overview of interactions in antibody-mediated and cell-mediated immunity Animation The antibody mediated immune response begins when a naive B cell encounters antigens from a pathogen, such as a bacterium. The B cell binds, processes, and displays this antigen. It is now an antigen-presenti...

Activation Energy - Valence Electrons

By: HWC, Views: 6100

■ Shared electrons in the outermost orbital form bonds. These electrons are called valence electrons. ■ Valence electrons are disrupted and can be rearranged into a new bond. ■ The energy necessary to start a reaction and break bonds is called the activation energy. ■ Reactants have...

Helper T cell receptors, activation, proliferation, differentiation & action

By: HWC, Views: 6753

• Most cells which have CD4 on their surface become Helper T cells (TN cells). • The CD4 1 cells only recognize a foreign antigen when it is presented with an antigen presenting immune cell (APC) that includes MHC-II protein. • The Helper T cell antigen receptor must match the presented...

T cell receptors

By: HWC, Views: 6344

• T cells are responsible for cell-mediated immunity. • Each T cell contains a unique form of T cell receptor (TCR) on its membrane. • These T cell receptors are produced through a process of genetic recombination which is able to produce millions of different variations. • Each T ce...

B cells and antibodies

By: HWC, Views: 7469

What Are Antibodies? Antibodies, also known as immunoglobulins, are Y-shaped proteins that are produced by the immune system to help stop intruders from harming the body. When an intruder enters the body, the immune system springs into action. These invaders, which are called antigens, can be vi...

The 4 steps of translation Animation

By: HWC, Views: 2500

Translation is the process of formation of a polypeptide chain according to codon present in mRNA. The four steps of translation are: Activation or charging of tRNA Initiation – recognition of start codon, binding of ribosomal subunits to mRNA and formation of initiation complex with Met-tR...

Action potentials - electrical characteristics and generation

By: HWC, Views: 6572

• An action potential is the nervous impulse or signal for long distance communication. Each action potential is generated at the cell's trigger zone. • Action potentials are considered an all-or-nothing phenomena because they are either generated or not. • The generation of an action...